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Dr. Friedrich Andreas Nobbe

ZENTREN	Clínica Juaneda
Sprachen	Spanisch Katalanisch Englisch Deutsch Französisch

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Geboren 1965 in Ulm, Deutschland. Studium der Philologie an der Universität Tübingen (Geschichte, Germanistik). Studium der Medizin an den Universitäten Gießen und Freiburg im Breisgau (Deutschland).

1994 Promotion zum Thema: „Posttraumatische Bewegungsstörungen – Langzeitergebnisse funktionell-stereotaktischer Eingriffe“, Universität Freiburg im Breisgau, Deutschland, Abschluss cum laude.

Facharztausbildung in Neurologie an den Universitätskliniken Lübeck (1994–1995), Barcelona (1995–1998) und Aachen (1998–2001).

1995–1998: Feodor-Lynen-Stipendium der Alexander von Humboldt-Stiftung zum Thema „Neurophysiologische Untersuchungen und neurophysiologisch gesteuerte Operationen bei Bewegungsstörungen wie z. B. Morbus Parkinson“. Hospital Clínic Barcelona, bei den Dres. Tolosa und Valldeoriola.

Seit 2001 wohnhaft auf Mallorca. Verheiratet, ein Kind.

Sprachen: Deutsch, Spanisch, Katalanisch, Englisch (fließend in Wort und Schrift), Französisch (gesprochen).

Alzheimer-Krankheit und Demenz: Behandlung mittels therapeutischer Apherese (AMBAR-Klinische Studie).

Parkinson-Krankheit:

Behandlung mittels tiefer Hirnstimulation Implantation von Neurostimulatoren Essenzieller Tremor Dystonie Behandlung der Spastik mittels intrathekaler Baclofen-Gabe

Innovation im Kampf gegen Alzheimer mit der AMBAR-Behandlung. Weitere Informationen.

Behandlung mittels tiefer Hirnstimulation bei Parkinson-Krankheit, essentiellem Tremor und Dystonie. Durchführung der ersten durch Tiefenhirnableitung gesteuerten Implantationen in Katalonien am Hospital Clínic Barcelona.

Durchführung der ersten Implantationen von Neurostimulatoren zur Behandlung der Parkinson-Krankheit am Krankenhaus Aachen (Aquisgran), Deutschland (2001).

Durchführung der ersten Implantationen von intrathekalen Baclofenpumpen in der Clínica Juaneda (2003).

Neurological examination Medical history (collection of current conditions), cranial nerve status, fundus of the eye, eye movements, strength, motor function, sensation, coordination, muscle tone, reflexes, gait, and balance. Memory and orientation.

Memory assessment Neuropsychological tests (e.g., for speech or memory disorders following traumatic brain injury, stroke, etc.). These tests evaluate perception, concentration, memory, and coordination. This method allows assessment of memory, spatial orientation, calculation ability, and executive functions. Psychological testing is performed, for example, to determine whether dementia is present, such as Alzheimer’s disease, and to assess its stage. It also helps detect other impairments of brain function, organic psychiatric syndromes, depression, or neuroses.

Psychopathological diagnosis Many neurological conditions are associated with psychological disturbances and require appropriate treatment. It is estimated that 50% of symptoms reported by patients in a neurological consultation are wholly or partially psychosomatic in nature.

Sleep laboratory Before treating a sleep disorder, it is essential to determine its type and identify any underlying causes. Successful treatment is based on a thorough examination and interview or prior diagnosis. If no diagnosis can be established, an evaluation in the sleep laboratory is recommended.

The first recordings of brain waves (EEG—electroencephalogram) in the 1930s helped expand our understanding of sleep by the late 1980s. EEG analysis allows real-time observation of brain activity, demonstrating that sleep is a dynamic process rather than a state similar to death.

Advances in sleep research are best reflected in the development of sleep laboratories. For sleep analysis, biological signals are recorded:

Brain waves: EEG (electroencephalogram) Eye movements: EOG (electrooculogram) Muscle tone: EMG (electromyogram)

Based on these recordings, sleep can be categorized into different phases, reflecting various physiological states. Today, five sleep phases are recognized, present to varying degrees in both healthy individuals and those with sleep disorders.

Additionally, oxygen saturation (pulse oximetry) is measured to diagnose sleep apnea syndrome (SAS) or to assess the effectiveness of a respiratory mask.

Sleep-deprived EEGs can be performed after appropriate deprivation in this clinic’s sleep laboratory, as well as polysomnography. Patients must undergo at least seven hours of sleep deprivation—remaining awake from 2:00 a.m. and arriving at 9:00 a.m. without having slept. Video EEG recordings of up to nine hours can also be performed at this clinic.

If this diagnostic method suggests a structural or respiratory sleep disorder, a full overnight sleep study can be arranged, conducted by the same specialist who performed the ambulatory sleep-deprivation test. This allows for a precise diagnosis and, if necessary, the recommendation of a respiratory mask, whose effectiveness will be tested and adjusted overnight during polysomnography.

Two self-assessment questionnaires will soon be available here to help identify the type and cause of sleep disorders.

Color duplex Doppler ultrasound Ultrasound examination of the neck blood vessels and cerebral arteries (transcranial through the temporal window) allows early detection of stroke risk and visualization of cerebral blood flow. Additionally, transorbital examination can visualize the blood supply to the eye via the ophthalmic artery.